Ravens vs Lions Prediction 9/22/25 NFL Picks Today

In this article we will formulate a Ravens vs Lions prediction for this NFL game on Monday, September 22nd at M&T Bank Stadium in Baltimore, Maryland. Let’s take a look at the prediction for this week 3 matchup.

Baltimore Ravens Betting Preview

The Baltimore Ravens are 1-1 this year after they defeated Cleveland by a score of 41-17 last week. Baltimore led 3-0 after the first quarter and 10-3 at the half, before scoring 31 of the first 38 points in the second half to pull away in the blowout victory. The Ravens were out gained by a total of 323-242, went 3-12 on first downs, and won the turnover battle by a total of 2-0 in the game. Lamar Jackson went 19-29 for 225 yards and four touchdowns, while Derrick Henry rushed 11 times for 23 yards. Zay Flowers was the leading receiver with seven catches for 75 yards in the win. The Baltimore defense recorded two sacks and seven tackles for loss in the victory. 

Baltimore started the season with a 41-40 loss on the road against Buffalo, where they blew a double-digit lead in the fourth quarter. The Ravens are averaging 40.5 points per game with 195.5 passing yards and 141.5 rushing yards per game, while they are allowing 29.0 points against per game this season. Lamar Jackson has completed 68.8% of his passes for 434 yards and six touchdowns, while Zay Flowers has caught 14 passes for 218 yards and one score. Derrick Henry has been the leading rusher with 29 carries for 192 yards and two touchdowns this year. 

Detroit Lions Betting Preview

The Detroit Lions are 1-1 this season after they defeated Chicago by a score of 52-21 in their last game. Detroit led 14-7 after the first quarter and 28-14 at halftime, before blowing the game wide open in the second half. The Lions out gained Chicago by a total of 511-339, went 4-10 on third downs, and won the turnover battle by a margin of 2-0 in the game. Jared Goff went 23-28 for 334 yards and five touchdowns, while Jahmyr Gibbs carried the ball 12 times for 94 yards and one score. Amon-Ra St. Brown led the Detroit receivers with nine catches for 115 yards and three touchdowns in the game. The Detroit defense recorded four sacks and five tackles for loss in the win. 

Detroit started the 2025 season with a 27-13 road loss against the Packers, in a game where they were absolutely dominated. The Lions are averaging 32.5 points per game with 267.0 passing yards and 111.5 rushing yards per game, while they are allowing 24.0 points against per game this season. Jared Goff has completed 80.6% of his passes for 559 yards, six touchdowns, and one interception, while Amon-Ra St. Brown has caught 13 passes for 160 yards and three touchdowns. Jahmyr Gibbs has led the rushing attack for Detroit with 21 carries for 113 yards and one score this season. 

Why the Lions will beat the Ravens

• The Lions have won eight of their last nine road games.
• The Ravens have lost three of their last four Week 3 games as home favorites.
• The Lions have covered the spread in each of their last 13 road games following a home win.
• The Ravens have failed to cover the spread in six of their last seven home games following a home win.
• The Ravens have lost the first quarter in five of their last six Week 3 games as home favorites.
• The Lions have won the first half in each of their last eight road games following a home win.
• The Lions have scored the first touchdown in each of their last six games as underdogs following a home win.

Total Points Facts

• Each of the Ravens’ last six home games against NFC North opponents have gone OVER the total points line.
• Five of the Lions’ last six games against AFC North opponents have gone UNDER the total points line.

Baltimore Ravens Player Prop Facts

• Derrick Henry has scored two touchdowns in three of the Ravens’ last four September games.
• Lamar Jackson has recorded 237+ passing yards in each of the Ravens’ last four games as home favorites with a total points line of at least 50.0.
• Lamar Jackson has recorded 20+ completions in each of his last seven home appearances against NFC opponents.
• Derrick Henry has scored at least one touchdown in each of the Ravens’ last seven games following a home win.
• Lamar Jackson has recorded 52+ rushing yards in seven of the Ravens’ last eight Monday games as favorites.
• DeAndre Hopkins has recorded 19+ receiving yards in each of his last 46 regular season appearances with his team as a home favorite.
• Derrick Henry has recorded 131+ rushing and receiving yards in each of his four previous Monday appearances with his team as a favorite.
• Heading into Week 3, Lamar Jackson ranks T1st in the NFL in passing touchdowns (6) this season.

Detroit Lions Player Prop Facts

• Jahmyr Gibbs has scored the first touchdown in three of the Lions’ last four games.
• Jahmyr Gibbs has scored two or more touchdowns in three of the Lions’ last four games with a total points line of at least 50.0.
• Jared Goff has recorded 26+ completions in five of the Lions’ last six games with a total points line of at least 50.0.
• Jared Goff has recorded 257+ passing yards in 13 of the Lions’ last 14 games following a home win.
• Jahmyr Gibbs has recorded 99+ rushing and receiving yards in each of the Lions’ last nine games against AFC opponents.
• Jahmyr Gibbs has recorded 68+ rushing yards in eight of the Lions’ last nine games against AFC opponents.
• Jahmyr Gibbs has scored at least one touchdown in each of the Lions’ last six games with a total points line of at least 50.0.
• Kalif Raymond has recorded 11+ receiving yards in each of his last 14 appearances with the Lions as underdogs.
• Heading into Week 3, Amon-Ra St. Brown ranks T1st in the NFL in touchdowns (3) this season.

Matchup/League Facts

• Ravens – two different players have recorded multi-touchdown games this season – equal-most in the NFL, heading into Week 3.
• Ravens – seven different players have recorded at least one touchdown this season – most in the NFL, heading into Week 3.
• Lions – two different players have recorded 50+ rushing yards in a game this season – equal-most in the NFL, heading into Week 3.
• Lions – one different players have recorded 80+ rushing yards in a game this season – equal-most in the NFL, heading into Week 3.

David Racey is 6-3 (67%) in his last nine NFL plays this season. Click here for his premium plays for this week!

Ravens vs Lions Prediction 

Both of these teams come into this matchup with a 1-1 record and both won easily at home last week. Baltimore has looked elite offensively to start the season when looking at their point totals, but they didn’t gain many yards last week against Cleveland. Detroit’s offense looked very strong last week against Chicago, but can Goff throw the ball downfield outside? We saw the Ravens dominate Detroit a couple of seasons ago in a similar situation, but I think Detroit can hang around in this game, as they are relatively healthy on defense. Take the Lions and the points here.